Formation of Extracellular Matrix-Digesting Invadopodia by Primary Aortic Smooth Muscle Cells
نویسندگان
چکیده
منابع مشابه
Formation of extracellular matrix-digesting invadopodia by primary aortic smooth muscle cells.
Invasion of the subendothelial space by vascular smooth muscle cells (VSMCs) contributes to the development and progression of diverse cardiovascular diseases. In this report we show that the expression of activated versions of Src, Cdc42 and Rac1, or a kinase-dead but open form of the p21-activated kinase (PAK1), induces primary rat aorta VSMCs to form extracellular matrix-degrading actin-rich...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2007
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.106.147744